Clinical pharmacology therapeutics journal

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You may amniotic sac medical treatment if you get some of the side effects. Do not be alarmed by the list of possible side effects. You may not experience any of them. The above alcoholic recovering includes the more common side effects of your medicine. They are usually mild and short-lived. Tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice any of the following:The above list includes very serious side effects.

You may need urgent medical attention or hospitalisation. Tell your doctor if you notice anything else that is making you feel unwell. Other side effects not listed above may also occur in some people.

Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well. Do not store Lipitor or any other medicine in the bathroom or near a sink.

Do not leave clinical pharmacology therapeutics journal tablets in the car or on windowsills. Heat and dampness can destroy some medicines. Keep your tablets where children cannot reach them. A locked cupboard at clinical pharmacology therapeutics journal one-and-a-half metres above the ground is a good place to store clinical pharmacology therapeutics journal. If your doctor tells you to stop taking Lipitor, or it has passed its expiry date, ask your pharmacist what to do with any tablets that are left over.

Each 20 mg tablet contains atorvastatin calcium equivalent to 20 mg atorvastatin. Each 40 mg tablet contains atorvastatin calcium equivalent to 40 mg atorvastatin. Each 80 mg tablet contains atorvastatin calcium equivalent to 80 mg atorvastatin. Excipients with known effect. For the full list of excipients, see Section 6. Lipitor is supplied as white, round, film coated tablets. Each tablet is debossed with the tablet strength on one side and 'ATV' on the other as follows: 10 mg: debossed '10' on one side and 'ATV' on the other.

Lipitor is indicated as an adjunct to diet for the treatment of patients with hypercholesterolaemia. Prior to initiating therapy with atorvastatin, secondary causes of hypercholesterolaemia (e. Lipitor is indicated in hypertensive patients with multiple risk factors for coronary heart disease (CHD) which may include diabetes, history of stroke or other cerebrovascular disease, peripheral vascular disease or existing asymptomatic CHD (see Section 5.

These effects do not replace the need to independently control known causes of cardiovascular (CV) mortality and morbidity such as hypertension, diabetes and smoking. Therapy should be individualised according to the target lipid levels, the recommended clinical pharmacology therapeutics journal of therapy and the patient's response.

Primary hypercholesterolaemia and mixed dyslipidaemia. The majority of patients are controlled with 10 mg Clinical pharmacology therapeutics journal once daily. A therapeutic response is evident within 2 weeks, and the maximum response is usually achieved within 4 weeks. The response is maintained during chronic therapy. Lipitor is for oral administration. It can be taken at any time of the day, with or without food.

Use in renal impairment. Use in hepatic impairment. Plasma concentrations of atorvastatin are materials construction increased in patients with chronic alcoholic liver disease (Child-Pugh B). The benefits of therapy should be weighed against the risks when atorvastatin is to be given to patients with hepatic insufficiency (see Section 4.

Use in combination with other medicinal compounds. Use of atorvastatin is not recommended in patients taking letermovir co-administered with ciclosporin. When atorvastatin and clinical pharmacology therapeutics journal are administered concomitantly, do not exceed 20 mg atorvastatin daily (see Section 4.

Appropriate clinical assessment is recommended to ensure that the lowest dose of atorvastatin necessary is used. Hypersensitivity to any component of this medication. Clinical pharmacology therapeutics journal liver disease or unexplained persistent elevations of serum transaminases (see Section 4. Pregnancy and lactation (see Section 4.

Women of childbearing potential, unless on an effective contraceptive and highly unlikely to conceive. Concomitant use with fusidic acid clinical pharmacology therapeutics journal Section 4. The incidence of these abnormalities was 0. Increases were generally not associated with jaundice or other clinical signs or symptoms. When the dosage of atorvastatin was reduced, or clinical pharmacology therapeutics journal treatment interrupted or discontinued, transaminase levels returned to pretreatment levels.

Most patients continued treatment on a reduced dose of Lipitor without sequelae.



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